Vitiligolike Leukoderma Associated With Chronic Unilateral Topical Ophthalmic Atropine and Dorzolamide

Francesco Bruni; Zaid Alsafi; Ali Abbas

doi:10.1001/jamaophthalmol.2026.1241

May 7, 2026JAMA Ophthalmology

Vitiligolike Leukoderma Associated With Chronic Unilateral Topical Ophthalmic Atropine and Dorzolamide

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Key Points

The aim is to report the occurrence of vitiligolike hypopigmentation associated with the use of topical atropine and dorzolamide.
Descriptive case report of the patient presenting with skin changes.
Assessment included the evaluation of treatment history and clinical features.
Analysis of the relationship between topical medications and skin condition.
The patient exhibited significant vitiligolike hypopigmentation after prolonged use of atropine and dorzolamide.
Eczematous dermatitis was also noted in conjunction with the pigment changes.

Implication

Case report details vitiligolike hypopigmentation in a patient using atropine and dorzolamide, suggesting a potential side effect.

Abstract

This case report discusses a patient with vitiligolike hypopigmentation and eczematous dermatitis associated with topical treatment with atropine and dorzolamide.

Discussion

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Cite This Study

Bruni et al. (2026) studied this question.

synapsesocial.com/papers/69fed090b9154b0b82877927 https://doi.org/10.1001/jamaophthalmol.2026.1241

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Vitiligolike Leukoderma Associated With Chronic Unilateral Topical Ophthalmic Atropine and Dorzolamide

Key Points

Implication

Abstract

Discussion

Cite This Study

Vitiligolike Leukoderma Associated With Chronic Unilateral Topical Ophthalmic Atropine and Dorzolamide

Key Points

Implication

Abstract

Discussion

Cite This Study

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