Structural characterization of phosphatidylcholine lipid monolayers across the liquid-expanded / liquid-condensed phase transition

Konrad Weber; Joshua Reed; Bastian Mueller; Chen Shen; Gerald Brezesinski; Emanuel Schneck

doi:10.1039/d6sm00208k

January 1, 2026Soft Matter

Structural characterization of phosphatidylcholine lipid monolayers across the liquid-expanded / liquid-condensed phase transition

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Key Points

This research aims to characterize the structural properties of phosphatidylcholine lipid monolayers during phase transitions.
Utilized controlled temperature experiments to assess lipid monolayer behavior.
Employed spectroscopic techniques for structural analysis of phase transitions.
Measured thermodynamic properties to evaluate the impact on membrane function.
Observed distinct structural ordering during phase transition between liquid-expanded and liquid-condensed states.
Identified significant changes in membrane dynamics related to the transition temperature.

Implication

Investigates structural changes of lipid monolayers, indicating crucial membrane dynamics.

Abstract

Lipid layers are the foundational element of biological membranes and can exhibit heterogeneous structural ordering that impacts membrane function. However, important thermodynamic aspects of transitions between fluid and ordered lipid...

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Cite This Study

Weber et al. (2026) studied this question.

synapsesocial.com/papers/69fed10fb9154b0b82878328 https://doi.org/10.1039/d6sm00208k

View Full Paper

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Structural characterization of phosphatidylcholine lipid monolayers across the liquid-expanded / liquid-condensed phase transition

Key Points

Implication

Abstract

Discussion

Cite This Study

Structural characterization of phosphatidylcholine lipid monolayers across the liquid-expanded / liquid-condensed phase transition

Key Points

Implication

Abstract

Discussion

Cite This Study

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