What question did this study set out to answer?

The aim is to detail the surgical steps for safely resecting C2 schwannomas with intracranial involvement.

May 9, 2026Open Access

How I do it: intracranially extended C2 schwannoma resection with tailored craniectomy

LGLorenzo GelminiUniversity of Brescia APAmedeo PiazzaMayo Clinic MFMarco Maria FontanellaUniversity of Brescia

Key Points

The aim is to detail the surgical steps for safely resecting C2 schwannomas with intracranial involvement.
Described surgical resection steps for extradural C2 schwannoma with intracranial extension.
Illustrated main surgical steps via an operative video.
Discussed indications, advantages, and complications specific to the approach.
Utilizing a tailored craniectomy enables effective resection of selected C2 schwannomas with intracranial extension.
The approach allows for safe management of complications related to the close relationship with the vertebral artery.

Abstract

Abstract Background C2 schwannomas are rare neoplasms presenting with variable extensions. Their possible intracranial involvement and close relationship with the V3 segment of the vertebral artery (VA) require a personalized and delicate surgical approach. Method We describe the resection steps of an extradural C2 schwannoma with intracranial extension. Indications, advantages, and approach-specific complications are discussed. The main surgical steps are illustrated in an operative video. Conclusion A tailored craniectomy adapted to the lesion intracranial extension enables a safe and effective resection of selected extradural, multicompartmental, cranially extended C2 schwannomas.

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