316 Frontiers Trial Finder: Implementing a mobile platform integrated with a Clinical Trial Management System to enhance accessibility and engagement

Objectives/Goals: A key barrier to clinical trial (CT) access is knowing which trials are enrolling. Frontiers has developed a Trial Finder mobile app that displays streamlined, up-to-date trial availability that can be integrated to other institutions. We’re gathering usability feedback and exploring interest from other institutions in adopting the tool. Methods/Study Population: The Frontiers Trial Finder app is a unique tool that extracts trial data and status directly from a Clinical Trial Management System (CTMS). It includes helpful links to ClinicalTrials.gov and provides ways to connect with the study team. The app updates automatically every night, storing the extracted data in a separate stream that can be accessed through the app or online. Its interface is custom-designed in-house and fully customizable, allowing the integration of additional resources such as FAQs, links to partner affiliates, and more. During onboarding, we identified two key efforts: first, organizing the trial directory by defining parent groups and subgroups; and second, encouraging research personnel to keep CTMS trial information current, as it now serves both operational and marketing purposes. Results/Anticipated Results: To organize the trial directory, we used the institution’s divisions as primary categories and disease types as subcategories. Since the CTMS previously didn’t capture ”disease type,” we added this field to the CT activation process. For studies already underway, we generated a report of currently enrolling trials. CTMS and CTSA staff collaborated to manually assign a disease type to each study. Going forward, adding a disease type to the directory will be a standard part of CT activation. Another challenge was that study teams were not accustomed to updating the CTMS when a study remained active but was no longer enrolling – largely because the CTMS had not been used for marketing. To support this shift, we launched a communication campaign to ensure all study teams understood and adopted the new expectations. Discussion/Significance of Impact: Depending on the state of an institution’s CTMS, onboarding this tool may require institutional messaging effort. However, the long-term advantages of automated data exchange significantly improve the efficiency of connecting volunteers to trials. Clinicians and volunteers alike can benefit from reliable, up-to-date trial availability.