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May 9, 2026The Journal of PhysiologyOpen Access

Modulation of pain by affective touch: effects of childhood trauma, depression, chronic pain, and spinal segment

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Authors

BABenedetta AlbinniMZMarisa ZimmermanVAVincent Alasha

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Overview

Randomized trial examines affective touch effects on pain perception in chronic pain patients, highlighting trauma and depression influence.

Key Points

  • This research aims to understand how different forms of touch affect pain perception, particularly in chronic pain conditions like fibromyalgia.
  • Investigated effects of gentle brushing and deep pressure on heat pain perception in controls and fibromyalgia patients.
  • Tested within-segment and between-segment touch-pain modulation effects.
  • Analyzed the influence of trauma history and depression on pain modulation outcomes.
  • Gentle brushing significantly reduced heat pain perception only in the between-segment condition, without differences between fibromyalgia patients and controls.
  • Trauma history and depression were identified as strong predictors of touch-pain modulation effects.
  • Overall, touch-pain modulation mechanisms seem preserved in fibromyalgia despite the pain condition.

Cite This Study

Albinni et al. (2026) studied this question.

synapsesocial.com/papers/69fed140b9154b0b8287879bhttps://doi.org/10.1113/jp290242
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