Key result
Case report describes a rare secundum ASD coexisting with RA and LV myxomas.
Why the study?
Coexistence of multiple myxomas and an atrial septal defect is rare.
Case Report (n=1)
Highlights the rare coexistence of multiple myxomas and an atrial septal defect, suggesting the need to evaluate for ASD when myxomas are present.
May support complete echocardiographic assessment in ASD or myxoma patients; leaves open shared pathogenetic mechanisms.
Myxoma is a common primary benign cardiac tumor that typically occurs in middle age. It is usually single and frequently found in the left atrium, particularly attached to the interatrial septum. An atrial septal defect (ASD) is a congenital defect, and myxomas often involve the interatrial septum. Therefore, the coexistence of these two conditions, especially when myxomas are multiple, is rare. We present a middle-aged man with a secundum-type ASD and two myxomas located in the right atrium and left ventricle, which were discovered incidentally. This implies that, in patients with one or multiple myxomas, it is essential to consider the potential presence of an ASD when searching for myxomas in the cardiac chambers.
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Radmanesh et al. (2026) conducted a case report in Simultaneous multiple myxomas and an atrial septal defect (n=1). A middle-aged man was incidentally found to have a rare coexistence of a secundum-type atrial septal defect and two myxomas located in the right atrium and left ventricle.
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