Purpose We are aimed at reporting a rare case of juxtafoveal microaneurysm in a young adult in the setting of paracentral acute middle maculopathy (PAMM) and discussing potential underlying mechanisms and therapeutic considerations. Methods This study describes a single case report and a treatment trial with nitroglycerin. Results We present a case of a 38‐year‐old male with recurrent migraines and juxtafoveal microaneurysm who was empirically treated with 0.4‐mg nitroglycerin, resulting in subjective visual improvement and resolution of the lesion on SD‐OCT. Conclusions This report highlights the potential role of nitroglycerin as a therapeutic option for recurrent PAMM, emphasizing the need for further investigation into its efficacy and safety.
No takes yet. Share an insight, caveat, or question.
Aghayeva et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: