Pulse Explorar nav.journalClub Debates Tendencias Investigadores

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

Inicio Explorar nav.journalClub Tendencias

⌘+K

All (animal) models (of neurodegeneration) are wrong. Are they also useful? | Synapse

November 20, 2018Open Access

All (animal) models (of neurodegeneration) are wrong. Are they also useful?

RRRichard M. RansohoffNorthwestern University

Puntos clave

Los puntos clave no están disponibles para este artículo en este momento.

Resumen

Richard M. Ransohoff, Entrepreneur-in-Residence at Third Rock Ventures and Visiting Scientist at Harvard Medical School, provides his personal opinion on using animal models to address current challenges and opportunities in drug development for neurodegeneration.

Preguntar a la IA

Me gusta

Guardar

Compartir

Ver artículo completo

Cite This Study

Richard M. Ransohoff (Tue,) studied this question.

synapsesocial.com/papers/69ff4d6a2ff633f36577760b https://doi.org/https://doi.org/10.1084/jem.20182042

Preguntar a la IA

Me gusta

Guardar

Compartir

Ver artículo completo

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease2010 · 2,102 citations
2Spreading of pathology in neurodegenerative diseases: a focus on human studies2015 · 797 citations
3Clinical Trials for Disease-Modifying Therapies in Alzheimer’s Disease: A Primer, Lessons Learned, and a Blueprint for the Future2018 · 183 citations
4Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice2016 · 463 citations
5The support of human genetic evidence for approved drug indications2015 · 1,778 citations