Why the study?
High admission blood glucose levels after acute myocardial infarction are common and associated with increased mortality regardless of diabetes status, but the mechanisms and role of intensive insulin treatment warrant review.
Does intensive insulin treatment improve prognosis in subjects with acute myocardial infarction and concomitant hyperglycaemia?
Does intensive insulin treatment improve prognosis in subjects with acute myocardial infarction and concomitant hyperglycaemia?
Acute hyperglycemia during myocardial infarction is a risk factor for increased mortality, highlighting the potential need for intensive insulin treatment.
High admission blood glucose levels after acute myocardial infarction are common and are associated with an increased risk of death in subjects with and without diabetes. In this review, the possible toxic action of acute hyperglycaemia is discussed in order to explain the worse prognosis in subjects with myocardial infarction and concomitant hyperglycaemia. The possible usefulness of intensive insulin treatment is also discussed.
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Antonio Ceriello (2004) studied this question.
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