Population
Cells, single organs, or the whole body, and actin filaments in vitro
Comparison
Myosin 1D (Myo1D) vs myosin 1C (Myo1C)
Design
Preclinical laboratory study
Authors
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Hypothesis-generating for laterality defects in congenital heart disease; leaves open clinical translation from animal models.
Myo1D acts as a chiral determinant sufficient to break symmetry at all biological scales through chiral interaction with the actin cytoskeleton.
Lebreton et al. (2018) studied this question.
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