Endothelial nitric oxide synthase utilizes a specific intracellular arginine pool derived from protein breakdown, which may accumulate endogenous inhibitors and explain the arginine paradox in endothelial dysfunction.
No takes yet. Share an insight, caveat, or question.
May account for arginine paradox in endothelial dysfunction; leaves open validation and targeting in human disease.
Simon et al. (2003) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: