Why the study?
Does immediate cardiac catheterization with PTCA improve ejection fraction compared to delayed PTCA in patients with acute myocardial infarction treated with thrombolytic therapy?
Does immediate cardiac catheterization with PTCA improve ejection fraction compared to delayed PTCA in patients with acute myocardial infarction treated with thrombolytic therapy?
Immediate catheterization and PTCA following thrombolytic therapy for acute MI provides no advantage in ejection fraction over delayed procedures and may increase bleeding and CABG risk.
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Immediate PTCA confers no EF benefit over delayed after thrombolysis; challenges routine early invasive strategy in AMI.
A 1988 study studied this question.