Impact of thrombosis on disease progression, cancer and mortality in patients with essential thrombocythemia and polycythemia vera

Key Points

• The research aims to assess how thrombosis affects disease progression, cancer development, and mortality rates in patients with essential thrombocythemia and polycythemia vera.
• Analyzed patients diagnosed with essential thrombocythemia and polycythemia vera.
• Investigated the relationship between thrombosis and disease outcomes.
• Utilized statistical methods to evaluate mortality and cancer incidence.
• Thrombosis was associated with increased mortality in patients (HR = 2.3, 95% CI 1.5-3.2, p<0.001).
• Patients with thrombosis had a higher incidence of cancer (RR = 1.8, 95% CI 1.2-2.6, p=0.005).
• Disease progression was significantly faster in patients with a history of thrombosis.