1142 Obstructive Sleep Apnea, Use of Positive Airway Pressure Therapy, and Dementia Incidence: A Longitudinal Study of Medicare Beneficiaries

Galit Levi Dunietz; Xiru Lyu; Henry Paulson; Ronald Chervin; Kerby Shedden; Tiffany Braley

doi:10.1093/sleep/zsag091.1141

May 1, 2026SLEEP

1142 Obstructive Sleep Apnea, Use of Positive Airway Pressure Therapy, and Dementia Incidence: A Longitudinal Study of Medicare Beneficiaries

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Key Points

This study aims to investigate whether obstructive sleep apnea (OSA) is a modifiable risk factor for dementia among Medicare beneficiaries.
Longitudinal analysis of fee-for-service claims from a random 20% sample of Medicare beneficiaries aged 65 and older (2010-2019) without dementia at baseline.
Obstructive sleep apnea and dementia diagnoses were identified using ICD-9/10 codes; PAP adherence defined using HCPCS codes for supplies.
Generalized estimating equations were employed to estimate cumulative dementia incidence by OSA status and PAP usage, adjusting for age, race, ethnicity, and deprivation index.
12.0% of women with OSA developed dementia by age 85, compared to 9.0% without OSA; 10.3% for men with OSA vs. 7.7% without.
Among OSA beneficiaries, dementia incidence was 10.3% for PAP adherent women versus 12.4% for non-adherent; for men, 8.8% vs. 10.7%.
PAP adherence suggested relative risk reductions of 17.4% in women and 17.6% in men, indicating partial mitigation of dementia risk.

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Implication

Longitudinal study assesses dementia risk in Medicare beneficiaries with obstructive sleep apnea and positive airway pressure therapy adherence, suggesting modifiable risks.

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Dunietz et al. (2026) studied this question.

synapsesocial.com/papers/6a002087c8f74e3340f9b541 https://doi.org/10.1093/sleep/zsag091.1141

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1142 Obstructive Sleep Apnea, Use of Positive Airway Pressure Therapy, and Dementia Incidence: A Longitudinal Study of Medicare Beneficiaries

Key Points

No abstract yet

Implication

Discussion

Cite This Study

1142 Obstructive Sleep Apnea, Use of Positive Airway Pressure Therapy, and Dementia Incidence: A Longitudinal Study of Medicare Beneficiaries

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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