Serum Prolidase in Myocardial Infarction: Purification, Kinetic Properties, and Drug-Enzyme Interactions

Key Points

• The aim is to isolate and purify prolidase from serum in myocardial infarction patients and assess its potential pharmaceutical inhibitors.
• Isolated and purified prolidase from patient serum samples
• Characterized enzyme's kinetic properties
• Evaluated drug-enzyme interactions using in silico methods
• Prolidase displayed specific kinetic characteristics relevant to myocardial infarction.
• Several pharmaceutical inhibitors were identified that interact with prolidase effectively.