Demonstrates efficient synthesis of γ-lactams in pharmaceuticals, highlighting potential clinical applications.
-aryl γ-lactams in good to excellent yields and diastereoselectivities under mild conditions. The potentiality of this method has been demonstrated in expedient synthesis of pharmaceutical drugs such as (±)-oxiracetam, (±)-phenotropil, (±)-phenibut.HCl, and (±)-pregabalin.
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Chowdhury et al. (2026) studied this question.
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