Corticosteroid Use in Orthognathic Surgery Practices: A Review of Literature

May 8, 2026

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Key Points

This review aims to evaluate the clinical efficacy and safety of corticosteroids, particularly dexamethasone, in orthognathic surgery.
Comprehensive review of randomized controlled trials, systematic reviews, and meta-analyses from 1974 to 2025.
Analysis focused on perioperative corticosteroid use in orthognathic procedures and its effects on postoperative outcomes.
A single intravenous dose of 8–16 mg dexamethasone significantly reduces postoperative edema, trismus, pain, and nausea and vomiting (PONV).
No increased risk of impaired wound healing or infection associated with corticosteroid use.
Corticosteroid administration in Enhanced Recovery After Surgery (ERAS) protocols improves comfort, reduces opioid use, and assists in quicker discharge.

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Review summarizes corticosteroid use to improve outcomes in orthognathic surgery, indicating potential benefits for patient recovery.

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Arslan et al. (2026) studied this question.

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