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May 10, 2026SLEEP0 citations

0530 Rural and Urban Differences in Obstructive Sleep Apnea Referrals in Primary Care

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JMJoscilin MathewHSHimani SanchetiBLBrittany Lapin

Key Result

Rural residence was associated with lower odds of receiving an obstructive sleep apnea referral compared to urban residence among high-risk primary care patients (OR 0.75; 95% CI 0.66-0.82; p<0.001).

Key Points

  • The study aims to investigate differences in obstructive sleep apnea referral rates between rural and urban patients in primary care settings.
  • Retrospective cohort study of adult patients assessed for OSA from 2017 to 2024
  • Inclusion of patients who received a sleep medicine consultation or a polysomnogram
  • Multivariable logistic regression to analyze the association between residence type and OSA referral, adjusting for demographic and socioeconomic factors.
  • 15% of rural patients referred for OSA evaluation vs. 20% of urban patients (p<0.001)
  • Rural patients had higher BMI (41.5 kg/m2 vs. 40.4 kg/m2; p=0.003) and were less likely to have government insurance (29.3% vs. 42.2%; p<0.001)
  • After adjustment, rural patients had lower odds of receiving an OSA referral (OR=0.75, 95% CI: 0.66, 0.82).

Study Design

Type

Cohort (n=25,917)

Multicenter

Yes

Structured PICO

Does rural residence reduce OSA referral rates in high-risk primary care patients compared to urban residence?

P
Population
25,917 adult patients at high risk for obstructive sleep apnea (OSA) seen in primary care at the Cleveland Clinic Health System (Ohio and Florida) from 2017 to 2024. High risk defined by comorbidities (obesity, heart failure, atrial fibrillation, hypertension, diabetes, cardiac arrhythmias, stroke, pulmonary hypertension, or coronary artery disease), BMI >35 kg/m2, and STOP score ≥2.
I
Intervention
Rural residence (n=3,874)
C
Comparator
Urban residence (n=22,043)
O
Outcome
OSA referral (sleep medicine consultation, polysomnogram, or type III order within 12 months of the primary care visit)

Patients at high risk for OSA in rural primary care settings are significantly less likely to be referred for evaluation than those in urban areas, highlighting geographic inequities in care access.

Main Result

Effect estimate: OR 0.75 (95% CI 0.66-0.82)

Absolute Event Rate: 15% vs 20%

p-value: p=<0.001

Abstract

Abstract Introduction Limited access to obstructive sleep apnea (OSA) evaluation has increased interest in primary care–based care models, yet structural and geographic factors may influence referral patterns. We hypothesized that OSA referral rates within primary care differ by patients’ geographic location after accounting for individual and neighborhood socioeconomic factors. Methods A retrospective cohort study was conducted using our electronic medical record to identify adult patients at risk for OSA who were seen in primary care at the Cleveland Clinic Health System (Ohio and Florida) from 2017 to 2024. We included patients who received either a sleep medicine consultation or a polysomnogram or type III order within 12 months of the primary care visit. High-risk patients for OSA were defined by the presence of at least one of these comorbidities: obesity(30 kg/m2), heart failure, atrial fibrillation, hypertension, diabetes, cardiac arrhythmias, stroke, pulmonary hypertension, or coronary artery disease; a BMI greater than 35 kg/m2; and a STOP score≥2. Rural-Urban Community Area codes were used to identify patients residing in rural and urban areas. Multivariable logistic regression was performed to examine the association between rural vs. urban residence and OSA referral, adjusting for age, sex, race, BMI, insurance, State, and Area Deprivation Index. Continuous variables were centered to mitigate multicollinearity. Results Of 25,917 patients at high risk for OSA, 3,874 were rural, and 22,043 were urban patients. Only 15% of rural patients were referred for OSA evaluation compared to 20% of urban patients (p 0.001). Among those referred, rural patients had a higher BMI(41.5 kg/m2IQR37.8–46.4vs40.4 kg/m2IQR 37.4–45.4; p=0.003), were less likely to be referred while on government insurance (29.3%vs42.2 %,p 0.001) and lived in neighborhoods with higher socioeconomic disadvantage (ADI, 7058–85vs6745–88;p 0.001) compared with referred urban patients. After the adjusted model, rural patients had lower odds of receiving an OSA referral compared to patients in urban areas (OR=0.75,95%CI:0.66,0.82). Conclusion Patients at high risk for OSA in rural primary care settings are less likely to be referred for evaluation than those in urban areas. These findings highlight the need to understand geographic-specific barriers to obtaining OSA evaluation to reduce inequities among rural populations. Support (if any)

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Cite This Study

Mathew et al. (2026) conducted a cohort in Obstructive Sleep Apnea (n=25,917). Rural residence vs. Urban residence was evaluated on OSA referral (sleep medicine consultation or polysomnogram/type III order) (OR 0.75, 95% CI 0.66-0.82, p=<0.001). Rural residence was associated with lower odds of receiving an obstructive sleep apnea referral compared to urban residence among high-risk primary care patients (OR 0.75; 95% CI 0.66-0.82; p<0.001).

synapsesocial.com/papers/6a002147c8f74e3340f9c155https://doi.org/10.1093/sleep/zsag091.0529
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