Demonstrates a new method for quantifying antihistamine drugs, suggesting improved accuracy in analysis.
A quick and convenient method has been developed for the micro estimation of antihistamine drugs. 1-5 mg of sample is allowed to react with 10 ml of 0.02 M, N-bromosaccharin solution. Unconsumed reagent can be accurately titrated with 5 ml of 15% KI and 0.02N sodium thiosulphate solution using starch as indicator. SD and CV was calculated for reproducible and accurate result. The accuracy of the method is within + 1 % and possible course of reaction was suggested on the basis of stoichiometry as well as find reaction product.
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Meera Prasad Verma (2025) studied this question.
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