ABCD2 score and secondary stroke prevention
Why the study?
Does the ABCD2 score reliably discriminate risk of early recurrent stroke in patients with suspected TIA?
Population
13,766 TIA patients from 29 studies published between January 2005 and September 2014
Design
Meta-analysis
Follow-up
7 days
Authors
Discussion
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Member takes
Implication
ABCD2 ≥4 lacks specificity for 7-day recurrent stroke; challenges score-based triage and supports urgent evaluation for all suspected TIA patients.
Structured PICO
Does the ABCD2 score reliably discriminate risk of early recurrent stroke in patients with suspected TIA?
P
Population
13,766 TIA patients from 29 studies published between January 2005 and September 2014
I
Intervention
Triage using ABCD2 score (dichotomized to </≥4)
O
Outcome
Recurrent stroke within 7 dayshard clinical
The ABCD2 score does not reliably discriminate low and high risk of early recurrent stroke or identify patients needing urgent intervention, indicating all suspected TIA patients require prompt specialist assessment.
Limitations
- 48% calculated the ABCD2 score retrospectively
- Few reported on the ABCD2 score's ability to identify TIA mimics
- Few reported use by nonspecialists
Cite This Study
Wardlaw et al. (2015) studied this question.