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February 15, 2022International Journal of Molecular SciencesOpen Access

TAMpepK Suppresses Metastasis through the Elimination of M2-Like Tumor-Associated Macrophages in Triple-Negative Breast Cancer

Chanju Lee Soyoung Kim Chanmi Jeong Inhee Cho Ju-Yeon Jo Ik‐Hwan Han Hyunsu Bae

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Abstract

T cells. Taken together, our findings suggest that TAMpepK could be a novel therapeutic agent for the inhibition of breast cancer metastasis by targeting M2-like TAMs.

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Lee et al. (2022) studied this question.

synapsesocial.com/papers/6a004b4164548b97a42d8045 https://doi.org/10.3390/ijms23042157

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Triple-Negative Breast CancerPrognostic Study · 2010 · 4,710 citations
2Triple-negative breast cancer molecular subtyping and treatment progress2020 · 2,462 citations
3CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophagesOriginal Research · 2015 · 652 citations
4A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and GrowthOriginal Research · 2009 · 662 citations
5Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Radiotherapy versus Chemo- and ImmunotherapiesReview · 2017 · 419 citations

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