Reduced deformability contributes to impaired deoxygenation‐induced ATP release from red blood cells of older adult humans

This is the authors' abstract. We don't add key points for this paper.

KEY POINTS: protein activation in RBCs from older adults. These findings are the first to demonstrate that the age-related decrease in RBC deformability is a primary mechanism of impaired deoxygenation-induced ATP release, which may have implications for treating impaired vascular control with advancing age. ABSTRACT: protein activation was similar in both groups (P > 0.05). We conclude that decreased RBC deformability is a primary contributor to age-related impairments in RBC ATP release, which may have implications for impaired vascular control with advancing age.