Why the study?
Patients with end-stage renal disease undergoing haemodialysis experience stressors leading to decreased quality of life, prompting a review to identify factors affecting health-related quality of life in these patients.
What is the health-related quality of life and what factors affect it in patients with end-stage renal disease undergoing dialysis?
What is the health-related quality of life and what factors affect it in patients with end-stage renal disease undergoing dialysis?
Patients undergoing dialysis experience measurable impacts on health-related quality of life, with mental health scores generally higher than physical health scores and significant geographic variation.
Dialysis patients show moderate HRQoL impairment with geographic variation; confirms burden and extends pooled evidence for targeted research.
BACKGROUND: Patients with end-stage renal disease undergoing haemodialysis experience a variety of stressors leading to decreased level of quality of life (QoL). Thus, in this study, we aimed to review the current literature and identify factors affecting the health-related QoL (HRQoL) in these patients. METHODS: A total of 147 studies were extracted from databases of Web of Science, PubMed, Scopus, Google Scholar, and Embase published between January 2000 and December 2020. Data were analysed using R software and results were reported with reference to Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards. RESULTS: A total of 623 728 patients undergoing dialysis participated in 147 studies in which QoL was assessed by means of two valid questionnaires, including Short-Form 36 (SF-36) and Kidney Disease Quality of Life (KDQOL)-short form V.1.3. Total HRQoL score for patients undergoing dialysis measured by KDQOL was 64.25 (95% CI 55.67 to 72.82). Based on SF-36, the mean score of mental health items was higher than the mean score of physical health condition. Furthermore, meta-regression based on the geographical place of residence revealed that the highest QoL in patients was observed in Japan, 66.96 (95% CI 63.65 to 70.28) and Brazil, 58.03 (95% CI 53.45 to 62.6). CONCLUSION: Studies conducted on HRQoL among patients undergoing dialysis recommend useful strategies to clinicians, letting them assess patients' QoL in terms of a wide range of physical, mental and environmental aspects.
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Raoofi et al. (2021) studied this question.
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