Translating an Antagonist of Chemokine Receptor CXCR4: From Bench to Bedside

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Bioluminescence Resonance Energy Transfer Reveals Ligand-induced Conformational Changes in CXCR4 Homo- and Heterodimers2005 · 262 citations
2. 2The chemokine SDF‐lα triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway1999 · 506 citations
3. 3Differential Functional Activation of Chemokine Receptor CXCR4 Is Mediated by G Proteins in Breast Cancer Cells2006 · 112 citations
4. 4The α-Chemokine, Stromal Cell-derived Factor-1α, Binds to the Transmembrane G-protein-coupled CXCR-4 Receptor and Activates Multiple Signal Transduction Pathways1998 · 622 citations
5. 5CXCL12/CXCR4 signaling activates Akt‐1 and MMP‐9 expression in prostate cancer cells: The role of bone microenvironment‐associated CXCL122005 · 246 citations