PURPOSE: drift in real time. THEORY AND METHODS: ) spectrum, and amide proton transfer weighted (APTw) image. RESULTS: spectra and APTw images than the conventional NFS-CEST sequence. Quantitatively, the compartmental-average APTw signals (mean ± standard deviation) from frontal white matter regions of all 26 human subjects were -0.32% ± 2.32% for the NFS-CEST sequence and -0.14% ± 0.37% for the FS-CEST sequence. CONCLUSIONS: drift correction without additional scan time and should be adopted on heavy-duty MRI scanners.
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Liu et al. (2019) studied this question.