INTRODUCTION: Drug delivery systems with extended-release profiles are ideal in improving patient compliance with enhanced efficacy. To develop devices capable of a prolonged delivery kinetics, it is crucial to understand the various underlying mechanisms contributing to extended drug release and the impact thereof on modulating the long-term performance of such systems in a practical application environment. AREAS COVERED: . EXPERT OPINION: conditions to methodically evaluate the eventual clinical efficacy.
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Wang et al. (2020) studied this question.
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