Why the study?
The study was conducted to compare the diagnostic performance of the original and 2018 Lake Louise criteria for diagnosing acute myocarditis and validate previously reported cutoff values for parametric mapping techniques.
Does the 2018 Lake Louise criteria improve diagnostic performance for acute myocarditis compared to the original criteria?
Does the 2018 Lake Louise criteria improve diagnostic performance for acute myocarditis compared to the original criteria?
The 2018 Lake Louise criteria improve the sensitivity of cardiac MRI for diagnosing acute myocarditis compared to the original criteria.
May support 2018 LLC for higher CMR sensitivity in suspected myocarditis; leaves open need for prospective validation before practice change.
PURPOSE: To compare the diagnostic performance of the original Lake Louise criteria (LLC) and the 2018 LLC for the diagnosis of acute myocarditis and simultaneously validate previously reported cutoff values for parametric mapping techniques. MATERIALS AND METHODS: A total of 40 patients with acute myocarditis and 26 control participants underwent cardiac MRI. Cardiac MRI protocol allowed for assessment of T2 signal intensity ratio, early gadolinium enhancement ratio, late gadolinium enhancement, T1 relaxation times, extracellular volume fraction, and T2 relaxation times. The original and the 2018 LLC were assessed, and differences between sensitivities and specificities were calculated with the McNemar test. RESULTS: = .999). CONCLUSION: Multiparametric cardiac MRI has a high diagnostic value for the diagnosis of patients clinically suspected of having acute myocarditis. The 2018 LLC further improve the diagnostic performance of cardiac MRI by increasing its sensitivity. An implementation of the new score into routine diagnostic protocols should be considered.
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Luetkens et al. (2019) studied this question.