The microbial metabolite desaminotyrosine protects from influenza through type I interferon

This is the authors' abstract. We don't add key points for this paper.

produced DAT and rescued antibiotic-treated influenza-infected mice. DAT protected the host by priming the amplification loop of type I IFN signaling. These findings show that specific components of the enteric microbiota have distal effects on responses to lethal infections through modulation of type I IFN.