Why the study?
Patients with diabetes have higher heart failure incidence and poorer prognosis, likely driven by diabetic cardiomyopathy whose complex underlying pathogenesis remains under active investigation.
Design
Review
Authors
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Should not yet change clinical practice in diabetic cardiomyopathy; extends mechanistic framework for future research.
This review summarizes the complex interplay of systemic, myocardial, and cellular/molecular mechanisms driving the pathogenesis of diabetic cardiomyopathy.
Salvatore et al. (2021) studied this question.
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