Population
Smooth muscle myosin (in vitro model)
Comparison
Cross-linking of myosin regulatory light chain… vs Single-headed myosin, uncross-linked myosin, or…
Design
Preclinical
Authors
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Preclinical findings only; leaves open the role of 10S myosin in human smooth muscle regulation or disease.
The study elucidates the structural requirements for the 10 S conformation of smooth muscle myosin, showing that nucleotide trapping requires both heads and specific tail-RLC interactions.
Olney et al. (1996) studied this question.
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