Why the study?
Does statin discontinuation increase 1-year all-cause mortality in survivors of a first acute myocardial infarction?
Population
9,939 patients surviving 90 days after their first acute myocardial infarction, mean age 68.4 ± 12.8 years…
Comparison
Statin discontinuation vs Non-users, continuous users, and starters
Design
Cohort
Follow-up
1 year
Authors
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Statin discontinuation after first MI warrants caution; leaves open whether effects are causal or modifiable in survivors.
Does statin discontinuation increase 1-year all-cause mortality in survivors of a first acute myocardial infarction?
Discontinuation of statin therapy after a first acute myocardial infarction is associated with a significantly increased risk of 1-year all-cause mortality.
Daskalopoulou et al. (2008) studied this question.
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