Demonstrates the potential of AOP-CTMP for predicting toxicity patterns in zebrafish, indicating a novel screening approach.
experiments. The individual-level effects predicted through AOP-CTMP showed strong consistency with actual observed toxicity patterns, confirming the reliability and practical potential of this approach. The results underscore that AOP-CTMP, enabling prediction of toxicity patterns from chemical perturbations, offers a novel and systematic strategy for key effects identification during toxicity screening.
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Fan et al. (2026) studied this question.
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