Real-world data on the impact of dose reduction measures on radiation exposure in CT perfusion of the brain

Large real-world cohort evaluating dose optimization measures in brain CT perfusion. Reduced tube current and longer sampling intervals lowered dose by up to 67.7%. Optimized protocols achieved radiation levels comparable to non-contrast head CT. Dose reduction translated into substantial decreases in estimated lifetime cancer risk. Benefits were most pronounced in younger patients undergoing CT perfusion imaging.