DNAzyme-Aptamer Electrochemical Biosensor for Pb(II) and Hg(II) Determination: Robust Validation in Food Matrices and Water Samples

Chang Su

doi:10.1039/d6ay00231e

January 1, 2026Analytical Methods

DNAzyme-Aptamer Electrochemical Biosensor for Pb(II) and Hg(II) Determination: Robust Validation in Food Matrices and Water Samples

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Key Points

The aim is to create a dual-recognition platform for the sensitive detection of lead and mercury ions in complex samples.
Developed a dual-recognition electrochemical biosensor.
Integrated a Pb(II)-dependent DNAzyme with an Hg(II)-specific aptamer.
Validated the platform using food matrices and water samples.
Achieved ultrasensitive detection of Pb(II) and Hg(II) in complex matrices.
Demonstrated high selectivity for toxic metal ions with minimal interference.

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Implication

Develops a biosensor for detecting toxic metals in food and water, highlighting sensitivity and selectivity.

Abstract

A dual-recognition electrochemical biosensing platform was developed for ultrasensitive and selective determination of trace toxic metal ions in complex matrices. The sensor integrates a Pb(II)-dependent DNAzyme and an Hg(II)-specific aptamer...

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Chang Su (2026) studied this question.

synapsesocial.com/papers/6a0172813a9f334c28272b49 https://doi.org/10.1039/d6ay00231e

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DNAzyme-Aptamer Electrochemical Biosensor for Pb(II) and Hg(II) Determination: Robust Validation in Food Matrices and Water Samples

Key Points

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Implication

Abstract

Discussion

Cite This Study

DNAzyme-Aptamer Electrochemical Biosensor for Pb(II) and Hg(II) Determination: Robust Validation in Food Matrices and Water Samples

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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