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September 13, 2021Journal of Medicinal ChemistryOpen Access

Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer

Xiaowei Luo Guodi Cai Yinfeng Guo Chenghai Gao Wei-Feng Huang Zhenhua Zhang Humu Lu Kai Liu Jianghe Chen Xiao‐Feng Xiong Jinping Lei Xuefeng Zhou Junjian Wang Yonghong Liu

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Abstract

DHODH inhibitor for further development of potent anticancer agents and a potential therapeutic strategy for TNBC.

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Luo et al. (2021) studied this question.

synapsesocial.com/papers/6a0193ac6f2c4fd2e25c9999 https://doi.org/10.1021/acs.jmedchem.1c01402

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