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Digital twinning presents an exciting opportunity enabling real-time optimization of the control and operations of cyber-physical systems (CPS) with data-driven simulations, while facing prohibitive computational burdens. This paper introduces a method, Sequential Allocation using Machine-learning Predictions as Light-weight Estimates (SAMPLE) to address this computational challenge by leveraging machine learning models trained off-line in a predictive simulation learning setting prior to a real-time decision. SAMPLE integrates machine learning predictions with data generated by real-time execution of a digital twin in a rigorous yet flexible way, and optimally guides the digital twin simulation to achieve the computational efficiency required for real-time decision-making in a CPS. Numerical experiments demonstrate the viability of SAMPLE to select optimal decisions in real-time for CPS control and operations, compared to those of using only machine learning or simulations.
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Goodwin et al. (2022) studied this question.
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