We set up a Grothendieck spectral sequence which generalizes the Lyndon–Hochschild–Serre spectral sequence for a group extension K → G → Q by allowing the normal subgroup K to be replaced by a subgroup, or family of subgroups which satisfy a weaker condition than normality. This is applied to establish a decomposition theorem for certain groups as fundamental groups of graphs of Poincaré duality groups. We further illustrate the method by proving a cohomological vanishing theorem which applies for example to Thompson's group F.
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Peter H. Kropholler (2006) studied this question.
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