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May 12, 2020Molecular Pharmaceutics

Selective Photokilling of Colorectal Tumors by Near-Infrared Photoimmunotherapy with a GPA33-Targeted Single-Chain Antibody Variable Fragment Conjugate

Danfeng Wei Ze Tao Qiuxiao Shi Lijun Wang Lei Liu Tianshan She Qin Yi Xiang Wen Lian Liu Shengfu Li Hao Yang Xian Jiang

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Abstract

< 0.001). Because the GPA33 antigen is specifically expressed in CRC tumors, A33scFv-IR700 might be a promising antibody fragment-photoabsorber conjugate for NIR-PIT of CRC.

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Cite This Study

Wei et al. (2020) studied this question.

synapsesocial.com/papers/6a02232b60baf37e2cd8ce5b https://doi.org/10.1021/acs.molpharmaceut.0c00210

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