Key result
Cardiovascular Risk in Young Finns Study expands to track cardiovascular risk across three consecutive generations.
Cohort (n=3,596)
Yes
The Cardiovascular Risk in Young Finns Study has been successfully expanded into a multigenerational cohort to study cardiovascular risk factors over a 40-year follow-up.
The longstanding national multicenter Cardiovascular Risk in Young Finns Study (YFS) was originally designed to provide information on cardiovascular risk factors and their determinants in children and adolescents of various ages in different parts of Finland [1, 2]. The first examination in 1980 recruited 3596 participants (49.1% boys) aged 3–18 years (mean age 10.4, 5.0 SD) from five cities and their surrounding rural communities. The cohort has been followed up eight times, with large-scale field studies in 1983, 1986, 1989, 1992, 2001, 2007, 2011, and 2018–2020. The participation rates have varied between 59% and 83%, and the cohort is dynamic, as the majority of those participants who have not participated in some of the follow-up studies have return to the study in later follow-up phases (Supplementary Fig. S7). In the latest follow-up study, the recruitment was extended to cover three consecutive generations: the original participants as well as their parents and offspring.
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Pahkala et al. (2025) conducted a cohort in Cardiovascular risk factors (n=3,596). The Cardiovascular Risk in Young Finns Study cohort of 3,596 participants followed since 1980 has been expanded to cover three consecutive generations including parents and offspring.
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