Key result
Conduction system pacing may improve functional outcomes (P=0.006) compared to right ventricular pacing after TAVR, with similar cardiovascular mortality.
Why the study?
Conduction system pacing has emerged as a physiological alternative to right ventricular pacing for patients developing conduction disturbances after transcatheter aortic valve replacement, but comparative data are needed.
Does conduction system pacing improve outcomes compared to right ventricular pacing in patients developing conduction disturbances after transcatheter aortic valve replacement?
Meta-Analysis
Does conduction system pacing improve outcomes compared to right ventricular pacing in patients developing conduction disturbances after transcatheter aortic valve replacement?
Conduction system pacing may improve functional outcomes compared to right ventricular pacing after TAVR without affecting overall survival.
Background: Conduction system pacing (CSP), including His bundle pacing and left bundle branch pacing, has emerged as a physiological alternative to right ventricular pacing (RVP) for patients developing conduction disturbances after transcatheter aortic valve replacement. Objective: We performed a systematic review and meta-analysis to compare CSP with RVP. Methods: statistics. The protocol was registered in PROSPERO (CRD420251125169). Conclusion: These findings suggest that CSP provides more physiological ventricular activation and may improve functional outcomes after transcatheter aortic valve replacement without affecting overall survival. Further randomized studies are warranted to confirm these observations.
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Deaconu et al. (2026) conducted a meta-analysis in Conduction disturbances after transcatheter aortic valve replacement. Conduction system pacing vs. Right ventricular pacing was evaluated (p=0.006). Conduction system pacing may improve functional outcomes (P=0.006) compared to right ventricular pacing after TAVR, with similar cardiovascular mortality.
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