Why the study?
Does intravenous nesiritide improve hemodynamic function and clinical status in patients hospitalized with decompensated congestive heart failure?
Population
432 patients hospitalized because of symptomatic decompensated congestive heart failure. Efficacy trial…
Comparison
Intravenous nesiritide infused at a rate of… vs Placebo for 6 hours or open-label standard…
Design
RCT, randomly assigned, double-blind and open-label
Follow-up
up to 7 days
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Supports nesiritide for acute decompensated HF; confirms hemodynamic and clinical benefits in this RCT.
Does intravenous nesiritide improve hemodynamic function and clinical status in patients hospitalized with decompensated congestive heart failure?
Intravenous nesiritide significantly improves hemodynamics and clinical symptoms in patients hospitalized with decompensated heart failure.
A 2000 study studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: