Objective: -CaMKII variants in neurodevelopmental disorders. Methods: variants on CaMKII structure and firing of neurons was evaluated by computational structural analysis, immunoblotting, and electrophysiological analysis. Results: currents, which facilitated spike repolarization of single action potentials. Interpretation: currents as a possible pathophysiological basis.
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Akita et al. (2018) studied this question.
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