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July 21, 2022RNAOpen Access

ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations

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Abstract

, ADAR RNA editing also suppresses responses to self dsRNA.

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Cite This Study

Hajji et al. (2022) studied this question.

synapsesocial.com/papers/6a02a230f1675f581a7549ea https://doi.org/10.1261/rna.079266.122

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Profiling RNA editing in human tissues: towards the inosinome AtlasOriginal Research · 2015 · 255 citations
2Identification of a selective nuclear import signal in adenosine deaminases acting on RNAOriginal Research · 2009 · 61 citations
3Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminaseOriginal Research · 1995 · 268 citations
4dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editingOriginal Research · 2000 · 196 citations
5ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticityOriginal Research · 2016 · 77 citations