What question did this study set out to answer?

To present a rare case of leukemia cutis as an initial sign of pre-B cell acute lymphoblastic leukemia in an infant.

May 12, 2026Pediatric Dermatology0 citations

Cutaneous Presentation of Pre‐B Cell Acute Lymphoblastic Leukemia in a 3‐Month‐Old Boy

LSLuke A. ScherzUniversity of Pittsburgh ETErika TvedtenCooper Medical School of Rowan University KHKim HooKim‐VickersCooper University Health Care

Key Points

To present a rare case of leukemia cutis as an initial sign of pre-B cell acute lymphoblastic leukemia in an infant.
A case report of a 3-month-old boy presenting with a solitary erythematous scalp nodule.
Diagnosis confirmed via biopsy and treatment administered based on findings.
Patient diagnosed with pre-B cell acute lymphoblastic leukemia from scalp nodule biopsy.
No systemic symptoms or abnormal laboratory findings observed prior to diagnosis.

Abstract

ABSTRACT We present a rare case of leukemia cutis as the sole presenting sign of pre‐B cell acute lymphoblastic leukemia in a 3‐month‐old boy. The patient exhibited a solitary, erythematous scalp nodule without systemic symptoms or abnormal peripheral laboratory findings, ultimately diagnosed via biopsy and treated successfully. This case highlights the importance of early dermatologic evaluation and biopsy in persistent or atypical infant scalp lesions.

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