BACKGROUND: , representing the lower and upper limit of the EARL recommendations). METHODS: were obtained and DS calculated. RESULTS: were investigated. CONCLUSION: Using the proposed updated EARL recommendations compared with the current recommendations will significantly change DS classification. In select cases, the discordance would affect the choice of medical treatment. Specifically, the current EARL recommendations were more often prone to classify patients as responders.
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Ly et al. (2019) studied this question.
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