Cryo-imaging analysis reveals SOS1-mediated sodium sequestration into plant vacuoles, indicating an intracellular storage role alongside plasma membrane transport.
exchanger 7; SOS1/NHX7) is to sequester sodium into vacuoles, rather than extrusion of sodium into the extracellular space. This is corroborated by the use of new genomic, complementing fluorescently tagged SOS1 variants. We show that, in addition to the plasma membrane, SOS1 strongly accumulates at late endosome/prevacuoles as well as vacuoles, supporting a role of SOS1 in vacuolar sodium sequestration.
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Ramakrishna et al. (2025) studied this question.