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March 30, 2023Advanced Materials74 citationsOpen Access

Multimodal‐Driven Magnetic Microrobots with Enhanced Bactericidal Activity for Biofilm Eradication and Removal from Titanium Mesh

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CMCarmen C. Mayorga‐MartinezJZJaroslav ZelenkaKKKarel Klíma

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Abstract

) nanoparticles as magnetic material allowing magnetic propulsion and covered these with polyethylenimine to load ampicillin and prevent the microrobots from disassembling. These microrobots exhibit multimodal motion as single robots as well as in swarms. In addition, they can transform from tumbling to spinning motion and vice-versa, and when in swarm mode they can change their motion from vortex to ribbon and back again. Finally, the vortex motion mode is used to penetrate and disrupt the extracellular matrix of Staphylococcus aureus biofilm colonized on titanium mesh used for bone restoration, which improves the effect of the antibiotic's activity. Such magnetic microrobots for biofilm removal from medical implants could reduce implant rejection and improve patients' well-being.

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Mayorga‐Martinez et al. (2023) studied this question.

synapsesocial.com/papers/6a0338bdbc3ffe278e6555e2https://doi.org/10.1002/adma.202300191
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