Why the study?
What are the incidence and predicting factors for paradoxical response in HIV-negative patients with isolated pleural tuberculosis receiving anti-tuberculosis treatment?
Population
458 HIV-negative patients diagnosed and treated with isolated pleural tuberculosis between March 2005 and…
Design
Cohort
Authors
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May identify high-risk pleural TB patients for closer monitoring; hypothesis-generating and requires validation before clinical use.
What are the incidence and predicting factors for paradoxical response in HIV-negative patients with isolated pleural tuberculosis receiving anti-tuberculosis treatment?
Paradoxical response occurs in 16% of HIV-negative patients with isolated pleural TB and is predicted by baseline pleural fluid eosinophil and protein levels.
Jeon et al. (2012) studied this question.