January 1, 2010Chemical Communications

Practical iron-catalyzed dehalogenation of aryl halides

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Authors

WCWaldemar Maximilian CzaplikTH Köln - University of Applied Sciences SGSabine GrupeUniversity of Cologne MMMatthias MayerRegensburg University of Applied Sciences

Abstract

An operationally simple iron-catalyzed hydrodehalogenation of aryl halides has been developed with 1 mol% Fe(acac)(3) and commercial t-BuMgCl as reductant. The mild reaction conditions (THF, 0 degrees C, 1.5 h) effect rapid chemoselective dehalogenation of (hetero)aryl halides (I, Br, Cl) and tolerate F, Cl, OR, SR, CN, CO(2)R, and vinyl groups.

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Czaplik et al. (2010) studied this question.

synapsesocial.com/papers/6a03613ec567d7abdf696efd https://doi.org/10.1039/c0cc01980a

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Practical iron-catalyzed dehalogenation of aryl halides

Abstract

Discussion

Cite This Study

Practical iron-catalyzed dehalogenation of aryl halides

Abstract

Discussion

Cite This Study

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