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Stuck on sensing: A method is presented for the immobilization of aryl diazonium modified biomolecules by direct electrografting onto the surface of a conducting material to create effective on-chip sensing layers (see picture). Proof of concept is given for both proteins (antibodies, enzymes) and DNA. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z605010_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Corgier et al. (2007) studied this question.
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